Protein Info for GFF433 in Variovorax sp. SCN45

Annotation: Flagellar brake protein YcgR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 251 PF07317: PilZN" amino acids 21 to 123 (103 residues), 87.8 bits, see alignment E=4.3e-29 PF07238: PilZ" amino acids 126 to 240 (115 residues), 43.7 bits, see alignment E=2.9e-15

Best Hits

Swiss-Prot: 71% identical to YCGR1_PARPJ: Flagellar brake protein YcgR 1 (ycgR1) from Paraburkholderia phytofirmans (strain DSM 17436 / LMG 22146 / PsJN)

KEGG orthology group: None (inferred from 72% identity to bxe:Bxe_A0149)

Predicted SEED Role

"Inner membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (251 amino acids)

>GFF433 Flagellar brake protein YcgR (Variovorax sp. SCN45)
MDTDPSNAQADAPDESAGNFGRRTPAEIGVQLRNLVNRSNNLTVQYAGGHLVTQLLDVDL
RRRVFTFDWGAQPEQNKGLLAARRCLFQAQPEGVRLEFSITTPREVRFEGLPAFEADFPE
VLVYMQRREYFRVDAPILDSFTCSGRLPPKGDPFSFEVQDLSLGGVGLRTKDVRVAELPL
GTRLLDCELSLGTLGQLTLDMQLVSQRATTLENGTLRYQLGFRFVTLPAGAETALQRLIT
RLEMKSRSLVG