Protein Info for GFF4324 in Xanthobacter sp. DMC5

Annotation: Putative FAD-dependent oxidoreductase LodB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 371 PF01494: FAD_binding_3" amino acids 9 to 187 (179 residues), 31.3 bits, see alignment E=2.6e-11 PF13450: NAD_binding_8" amino acids 13 to 45 (33 residues), 22.8 bits, see alignment 1.8e-08 PF04820: Trp_halogenase" amino acids 86 to 366 (281 residues), 39.9 bits, see alignment E=5e-14

Best Hits

Predicted SEED Role

"Dehydrogenase flavoprotein LodB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (371 amino acids)

>GFF4324 Putative FAD-dependent oxidoreductase LodB (Xanthobacter sp. DMC5)
MSGPASSRVGVAIIGAGPAGCATAIALARRGIGDVALFDAGAGDGPRIGETIPGAALPLL
SRLGLMDRFATRGHLPALGSTAVWGKAEPHHSDGFANPFGGGWHLDRAGFDADLRAEAMA
MGVPLHSGRLRMMAPEGAGHRLRFEGADGPFEITAGLVVDASGVRAAALRSLKVARNSVD
AIAFHWTFLALTEPEAVPARTFLEAAPDGWWYASRIPGGRAVLGLATDPDTGARFADAAA
FRAALADTRLIGPEIARGRPEDTEAPPRIAIAPTAILSAVAGPGWLAVGDAAACLDPLLS
QGLTRALEDGIAAADAIAGALAGEDGALRMYQDRVFARFTAGVRLRAAFYATEARWPDAP
FWRRRQVQAAA