Protein Info for GFF431 in Xanthobacter sp. DMC5

Annotation: Sialic acid TRAP transporter large permease protein SiaM

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 468 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 45 to 64 (20 residues), see Phobius details amino acids 69 to 89 (21 residues), see Phobius details amino acids 94 to 119 (26 residues), see Phobius details amino acids 131 to 159 (29 residues), see Phobius details amino acids 163 to 190 (28 residues), see Phobius details amino acids 207 to 228 (22 residues), see Phobius details amino acids 234 to 296 (63 residues), see Phobius details amino acids 314 to 335 (22 residues), see Phobius details amino acids 353 to 386 (34 residues), see Phobius details amino acids 396 to 424 (29 residues), see Phobius details amino acids 436 to 460 (25 residues), see Phobius details PF06808: DctM" amino acids 6 to 456 (451 residues), 419.3 bits, see alignment E=8.4e-130

Best Hits

KEGG orthology group: None (inferred from 90% identity to azc:AZC_2418)

Predicted SEED Role

"TRAP-type C4-dicarboxylate transport system, large permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (468 amino acids)

>GFF431 Sialic acid TRAP transporter large permease protein SiaM (Xanthobacter sp. DMC5)
MWLLIGGFLFLMLCGVPVAIAMAGASLVYILVSGTVPDVVIAQRMIAGVESFPLLAVPFF
ILAGNLMNIAGVTGRIYAFAVALVGWMRGGLGQVNIIGSVIFSGMSGTAIADAAGLGTIE
IKAMKDHGYSTEFAVGVTAASATLGPIIPPSLPFVIYGMLANVSIGALFLGGVVPGVVMT
LLMMGTVAYFAHRNGWGSDAAFNWRQLLSASIEVVIVLAFPAAVYVMIEVGLSTNQAVLI
ALAVLIALDWYFDFSAVMALMTPVILIGGMTLGWFTPTEAAVAAVIWSLFLGLVRYRSMT
LKTLAKATFDTIETTASVLFIVTAASIFAWLLTASQAAQMLSDAILGFTQNKWVFLALAN
LLILFVGCFIDTIAAITILVPILLPIVLKLGIDPIHFGLIMTLNLMIGLLHPPLGMVLFV
LARVARLSVERTTMAILPWLVPLMIALLAITYIPGLTLWLPHAMGLGR