Protein Info for PS417_22010 in Pseudomonas simiae WCS417

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 transmembrane" amino acids 28 to 48 (21 residues), see Phobius details amino acids 80 to 100 (21 residues), see Phobius details amino acids 108 to 126 (19 residues), see Phobius details amino acids 132 to 155 (24 residues), see Phobius details amino acids 167 to 188 (22 residues), see Phobius details amino acids 200 to 217 (18 residues), see Phobius details amino acids 284 to 305 (22 residues), see Phobius details amino acids 320 to 338 (19 residues), see Phobius details amino acids 348 to 366 (19 residues), see Phobius details amino acids 371 to 389 (19 residues), see Phobius details amino acids 409 to 430 (22 residues), see Phobius details amino acids 436 to 457 (22 residues), see Phobius details PF00083: Sugar_tr" amino acids 38 to 469 (432 residues), 126.9 bits, see alignment E=1.1e-40 PF07690: MFS_1" amino acids 70 to 329 (260 residues), 69.4 bits, see alignment E=2.8e-23 amino acids 325 to 461 (137 residues), 42.4 bits, see alignment E=4.4e-15

Best Hits

KEGG orthology group: K08369, MFS transporter, putative metabolite:H+ symporter (inferred from 97% identity to pfs:PFLU4817)

Predicted SEED Role

"Transporter, MFS superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U5N4 at UniProt or InterPro

Protein Sequence (470 amino acids)

>PS417_22010 MFS transporter (Pseudomonas simiae WCS417)
MSTLTSTTDGIDPIRAAHISARIDRLPAVATVWRLVALLSIGGFFELYDLFQTAYISPGL
ISDGIFHTGSEGVFGFSDQAAFASATFLGLFLGASLLSPIADRYGRRAIFTFALVWYTVA
TVLMGIQTSALGIICMRFLVGIGLGIELVTIDAYLSELVPKRMRSSAFAFAFFIQFLSVP
AVALMSWWLVPQAPFGVSGWRWVVLSSAVFALFIWQLRKRLPESPRWLAQKGRFEEAGVI
MDSLEARCQKDHGKPLDEPEPETVSVQGSGRFADIWQPPYRRRALMLIVFHVFQAIGFFG
FGNWLPALLSGQGVSVTHSLLYAFIITLAYPLGPLLFVKVANRFENKWQIVGSALGAVIF
GSLFALQTTAVGLVICGVMITFCNAWLSFSYHSYQSELFPTNIRARAVGFCYSFSRLSTV
FSSLLIGFILEHLGTPGVLAFIASSMLIVMITISWFGPRTRNLALENIAH