Protein Info for GFF4298 in Sphingobium sp. HT1-2

Annotation: IncF plasmid conjugative transfer protein TraG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1092 transmembrane" amino acids 34 to 54 (21 residues), see Phobius details amino acids 59 to 80 (22 residues), see Phobius details amino acids 327 to 352 (26 residues), see Phobius details amino acids 365 to 387 (23 residues), see Phobius details amino acids 416 to 441 (26 residues), see Phobius details PF07916: TraG_N" amino acids 5 to 457 (453 residues), 369.1 bits, see alignment E=4e-114 PF01551: Peptidase_M23" amino acids 986 to 1082 (97 residues), 96.9 bits, see alignment E=6.7e-32

Best Hits

Predicted SEED Role

"IncF plasmid conjugative transfer protein TraG" in subsystem Type 4 secretion and conjugative transfer

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1092 amino acids)

>GFF4298 IncF plasmid conjugative transfer protein TraG (Sphingobium sp. HT1-2)
MGALEVFTIGGGEYIVNVFNAVAAWTGGGGYRSLLQVVMVMGFIYSLFIVAFSLDWRAWF
NWFLQSTLIYMMLMVPTVTVKVTDRINPTLAPAVVDNVPLGLGVMASFTSQVGDWMTRTA
ETVFVMPNALSLSTNGMIYGARLMDKARTFQITDSVFRANLDEHLKQCTFYDVLLGFKSM
DDLTRSTNVWEAIGPGSPARSQRWIASAGPGTTENTIIPCNEAYSRLDGQWQAAFDKDLI
PFARSAYPGLSDAVAAQKIRDDLPIVAAQMHGTPSDAYTYLRQVSMIDAFLAARESFSDA
GWDAYAAQRADAQAKNTYTSIATQAMTWVPLLGIVLTVVFYAMFPVLFPLFLFPRTGIQT
LKGYGTGFFYLASWGPLYVILHMFVMSRAAALYHGVSPTGPTLLVSDGMANVNESISTLA
GFLMMSVPFIAGGMARGAMAIAGHATSMLQPAQSAAEQAATERTTGNYSYGNTSFQNLTS
GMTQSNKWDTQPKYNDGFAVGSYTNADGGITYGFADGSNAFDTRQGISNLSFTPTRTSGF
DSQMSRALSEGQSHTQSLRNSASQSWNATATTATDLLSAAEHRRGSSTETGSGFNNSVAR
MTDVSRSLSSGLTSKFGLTESDSQQVARATQMTGDANAGIEALASVWKNKFADVGVKGGL
GVRLASIASENTGRTISGDQAYSELKDYLTKETNSTQARAARDEFMRETSTSGDSEVRSL
SQKLGVSVGESRSASLEATRAEETFQRVSQDVRESEQRGWSLNRNESQEFVVYAQERLLN
DPTLSQFNWTPGMVMPRTREQEQVRDILLGEFMERKVASVREELGVTIPGQLDNSLHGPA
STTAGGVQQWGERRAAGIRAQGPEVSIRESSRDTGLAGEVADAIPNASVRITHGAFEIGN
GVDEAKGTAAQIGKHVQERNDAWITTTLPGVESIRDTARDRLGIGQGTSHVYELPRGERA
TLPISGRLTSNMGGRVDPVTGQPGHHHRGVDIAQRAGAPIPAPASGRVVKNDFQANGAGN
YIVLEHGDGSQSKYFHMQDRSRFPVGSTIEQGEILGRVGSSGKSTGPHLHYELWKDGAPV
DPRRFQLRNGRG