Protein Info for GFF4290 in Sphingobium sp. HT1-2

Annotation: Error-prone repair protein UmuD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 148 PF00717: Peptidase_S24" amino acids 25 to 139 (115 residues), 73.4 bits, see alignment E=6.2e-25

Best Hits

KEGG orthology group: K03503, DNA polymerase V [EC: 3.4.21.-] (inferred from 40% identity to dvu:DVU2907)

Predicted SEED Role

"Error-prone repair protein UmuD"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (148 amino acids)

>GFF4290 Error-prone repair protein UmuD (Sphingobium sp. HT1-2)
MSTCVIPLSRPVPIAHIPTDLCLKIVSAAGAGFPSPAQDWEETAVNLVELLRLDRAASFV
FRVSGHSMLDAGIHDDDVVVVDRDVTPSNGRIVIAVVDGGFVIRQLVWREGKPTLEARNA
RMRYEPVVADEAVEIWGVVRATVRNLQG