Protein Info for GFF4277 in Sphingobium sp. HT1-2

Annotation: Na(+) H(+) antiporter subunit G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 25 50 78 transmembrane" amino acids 7 to 28 (22 residues), see Phobius details amino acids 48 to 75 (28 residues), see Phobius details PF03334: PhaG_MnhG_YufB" amino acids 12 to 75 (64 residues), 68.9 bits, see alignment E=1.8e-23

Best Hits

KEGG orthology group: K05571, multicomponent Na+:H+ antiporter subunit G (inferred from 68% identity to bja:bsr7317)

Predicted SEED Role

"Na(+) H(+) antiporter subunit G" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (78 amino acids)

>GFF4277 Na(+) H(+) antiporter subunit G (Sphingobium sp. HT1-2)
MSGLGDIATIVLVSAGALLFLAGALGLLRFPDTLSRLHAISKADNLGLGLIVLGLLPQMA
SIADGLKLLCIWLLAQLS