Protein Info for GFF4263 in Variovorax sp. SCN45

Annotation: TonB-dependent siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 820 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF07660: STN" amino acids 69 to 115 (47 residues), 40.3 bits, see alignment 3.2e-14 PF07715: Plug" amino acids 162 to 261 (100 residues), 73.8 bits, see alignment E=2.3e-24 TIGR01783: TonB-dependent siderophore receptor" amino acids 164 to 820 (657 residues), 327 bits, see alignment E=1.4e-101 PF00593: TonB_dep_Rec_b-barrel" amino acids 375 to 789 (415 residues), 166.7 bits, see alignment E=2.6e-52

Best Hits

Predicted SEED Role

"TonB-dependent siderophore receptor" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (820 amino acids)

>GFF4263 TonB-dependent siderophore receptor (Variovorax sp. SCN45)
MRQSRPVPARFSKLAPLALAAALAAGLCGPAQAQASAAFHTSRDLAIGAQAMGPALNELA
RQAGLQLMFPPALVAGKTAPAVSGRLTPRQAVDRLLAGSGLAAELNGDAVVVKPAPPAAA
GDHSTLPAVTVSAEGPSDGITESTGSYTTRATGAGTRMALSLRETPQSVSVVGRQQIEDQ
NLTTLVDVLRQTPGIVADRLDERVSFSSRGFALGTMIDGVPTLSYNTVAGESSMASTSIY
DRVEVIRGAAGLLNGAGSPGGSVNLVRKRPTAEFSGHVTAGFGSWNRYTSEVDVGGSLNA
AGTVRGRVVASHTAGDSFIENKKQREDVFYGIAEMDVAPGTLLTAGYEYQKTGIDGANFG
QAPLFYRNGLATQLPRSYNSSTPWSTWDMTTQRLFVNLDHRFGNGWRLKADAAYAKNDRE
RFSGDLWLYPANISPSANLGLVQLANNPANSTNKSLDVYATGPFDLFGRTHEASVGFNIN
RYDYGYGNWGAVPNAFDRRTVSIFSLGSIAQPAFNYPLNHFDGTTEEKGLYAAARFKPLD
ALSVLVGGRVSWYENQSSQRLWTNGTRGALVTNKPVKEDAVFTPYVGVVYDLSKEYSLYA
SYTDIFQPNTVRDASNQVLDPKRGTNSELGIKGEHWGGRLNTSFAVFRTQEDNLAVLDSG
APLLADGTAPYRAVKGARSKGFEFTVSGELARGWQVMGGYTYHAKRDNKDVLLNPTYPRR
LFRVATSYRFPGDWSALTIGGSVSYQSDIYYDESYGTGRATQGGLTLISLMARYEFSKQL
SATLNIENLSDKRYYTGLGGYNGYTYGAPRNAWLKATYKF