Protein Info for PS417_21825 in Pseudomonas simiae WCS417

Annotation: hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 349 PF13483: Lactamase_B_3" amino acids 78 to 285 (208 residues), 38.3 bits, see alignment E=1.4e-13 PF12706: Lactamase_B_2" amino acids 94 to 285 (192 residues), 152 bits, see alignment E=1.7e-48

Best Hits

KEGG orthology group: None (inferred from 94% identity to pfs:PFLU4780)

Predicted SEED Role

"Outer membrane protein romA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U0M4 at UniProt or InterPro

Protein Sequence (349 amino acids)

>PS417_21825 hydrolase (Pseudomonas simiae WCS417)
MATISSRVDSSPAAPKQDQGHFSNEAPVQQGGFGKTLRIFWNMLFNKPRSTRPVGQIPVQ
PLTHEQLLAAPDHSVFRLGHSTVLLKMRGKFWVTDPVFAERASPFSWAGPKRFHPPPISL
EELPPLEAVILSHNHYDHLDRKAVVQLADKTRYFLAPLGVGDILVKWGVDASKVRQLDWW
QGTEVEGIRFVATPAQHFSGRGLLDANQTLWCSWVMIDGARRIFFSGDTGYFDGFKRIGE
QYGPFDLTLMETGAYNVDWPHVHMQPEQTLQAHIDLKGRWLLPIHNGTFDLAFHAWHEPF
DRIMALAWERNVCITTPQMGQAFSLNQPERGCAWWLEVEAQGAQEQLAG