Protein Info for GFF4254 in Xanthobacter sp. DMC5

Annotation: Polyphosphate:AMP phosphotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 495 TIGR03708: polyphosphate:AMP phosphotransferase" amino acids 2 to 494 (493 residues), 597 bits, see alignment E=2.8e-183 PF03976: PPK2" amino acids 12 to 232 (221 residues), 107.7 bits, see alignment E=3.4e-35 amino acids 271 to 492 (222 residues), 273.3 bits, see alignment E=8.6e-86

Best Hits

KEGG orthology group: None (inferred from 83% identity to xau:Xaut_2483)

Predicted SEED Role

"UDP-galactose-lipid carrier transferase (EC 2.-.-.-)" (EC 2.-.-.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.-.-.-

Use Curated BLAST to search for 2.-.-.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (495 amino acids)

>GFF4254 Polyphosphate:AMP phosphotransferase (Xanthobacter sp. DMC5)
MFESATFAHHLDKAAFKAMEPSLREDLLTAQFQLIEQKRRSLIVLIHGPDGAGKGAVLNR
LYGWLDVRKLQTLTFDMPCAREDRPAMWKYWRELPPFGQIGIMLGSWYHAPLCKRALDEM
KRGDFMAALEDIQRFEAMLHAEGVSLLKIWLYLDPEEARARLKGVTKGEWQRPVVREWEE
LKGSGPRKRLLAISEDAARATSTETSPWHVVPAADEEYRDAMAGSLLLEKLRSMVAEPEP
APQPLAPNPTQLPSTLPTFSILSTLDLSKSLDEDDYDRQLAQEQSRITRLTNSPRFADAG
LVVAFEGSDAAGKSSTIMRLRRALDPRHFRVHPIAAPTDEERARPYLWRFWRHIPTHGRT
AIFDRSWYGRVLVERVERLCGPDDWGRAYGEINDFEAQLSAANYVVVKFWLAISQQEQAR
RFEERETVAYKRFKLTPEDWRNREKWPLYEAAVTEMVDRTSTRIAPWTLVESEDKRYGRV
KVLKTIADRLQQALG