Protein Info for PS417_21790 in Pseudomonas simiae WCS417

Annotation: arginine ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 PF00005: ABC_tran" amino acids 20 to 178 (159 residues), 117.7 bits, see alignment E=6.1e-38 PF13304: AAA_21" amino acids 142 to 209 (68 residues), 27.3 bits, see alignment E=3.8e-10

Best Hits

Swiss-Prot: 52% identical to NOCP_AGRFC: Nopaline permease ATP-binding protein P (nocP) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K02028, polar amino acid transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 96% identity to pfo:Pfl01_2854)

Predicted SEED Role

"ABC transporter ATP-binding protein"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.21

Use Curated BLAST to search for 3.6.3.21

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UMA6 at UniProt or InterPro

Protein Sequence (254 amino acids)

>PS417_21790 arginine ABC transporter ATP-binding protein (Pseudomonas simiae WCS417)
MRSIVKAVNLNKYYDQYHALRDINIEVEQGEVMCIIGPSGSGKSTLLRCVNQLEKIDKGG
LWVDGELVGYRVVGNKLHEMNESQIARQRLATGMVFQRFNLFPHMTVLQNIIEGPCQVLK
RSPKEAIEDALELLARVGLADKRNAYPVELSGGQQQRVAIARALAMRPKLMLFDEPTSAL
DPELVGEVLSVMRDLATTGMTMIVVTHELGFAREVSNRMVFMDAGQIVEAGSPEEILISP
QNPRTQSFISAVRT