Protein Info for GFF424 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Putative glycosyl hydrolase of unknown function (DUF1680)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 651 PF07944: Beta-AFase-like_GH127_cat" amino acids 12 to 427 (416 residues), 367.7 bits, see alignment E=1.1e-113 PF20736: Glyco_hydro127M" amino acids 438 to 532 (95 residues), 83.7 bits, see alignment E=1.2e-27 PF20737: Glyco_hydro127C" amino acids 534 to 649 (116 residues), 84.9 bits, see alignment E=3.7e-28

Best Hits

KEGG orthology group: K09955, hypothetical protein (inferred from 100% identity to stm:STM3679)

Predicted SEED Role

"Putative glycosyl hydrolase of unknown function (DUF1680)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (651 amino acids)

>GFF424 Putative glycosyl hydrolase of unknown function (DUF1680) (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MNVLEVDLHKLTVSDPFLGQYQQLVRDVVIPYQWDALNDRIPEAEPSHAIENFRIAAGQQ
TGDFYGMVFQDSDVAKWLEAVAWSLCQKPDPALEKTADEVIELVAAAQCDDGYLNTYFTA
KAPQERWSNLAECHELYCAGHLIEAGVAFFQATGKRRLLDVVCRLADHIDSTFGPGENQL
HGYPGHPEIELALMRLYEVTEQPRYMTLASYFIGQRGAQPHFYDEEYEKRGQTSYWHTYG
PAWMVKDKAYSQAHLPISQQQTAIGHAVRFVYLMTGVAHLARLSNDEGKRQDCLRLWKNM
AQRQLYITGGIGSQSSGEAFSSDYDLPNDSVYAESCASIGLMMFARRMLEMEADSQYADV
MERALYNTVLGGMALDGKHFFYVNPLEVHPKSLKFNHIYDHVKPIRRRWFGCACCPPNIA
RVLTSLGHYIYTPRADALYINMYVGNSMEIPVENGALKLRISGNYPWHEQVKIAIDSVQP
VRHTLALRLPDWCPEAKVTLNGLDVEQDIRKGYLHIRRTWQEGDTITLTLPMPVRRVYGN
PLARHVAGKVAIQRGPLVYCLEQADNGEELHNLWLPKESEFRVFEGKGLFAHKMLIQAEG
EKQSAPDAQHQALWHYDNAPSSRQPQTLTFIPWFSWANRGEGEMRIWVNER