Protein Info for GFF4236 in Sphingobium sp. HT1-2

Annotation: Capsular polysaccharide ABC transporter, ATP-binding protein KpsT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 217 PF00005: ABC_tran" amino acids 21 to 150 (130 residues), 61.9 bits, see alignment E=5.3e-21

Best Hits

Swiss-Prot: 59% identical to CTRD_NEIMA: Capsule polysaccharide export ATP-binding protein CtrD (ctrD) from Neisseria meningitidis serogroup A / serotype 4A (strain Z2491)

KEGG orthology group: K09689, capsular polysaccharide transport system ATP-binding protein (inferred from 65% identity to rsl:RPSI07_2506)

Predicted SEED Role

"Capsular polysaccharide ABC transporter, ATP-binding protein KpsT" in subsystem Capsular Polysaccharide (CPS) of Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (217 amino acids)

>GFF4236 Capsular polysaccharide ABC transporter, ATP-binding protein KpsT (Sphingobium sp. HT1-2)
MIVLDGVTKSYHTRAGPKHVLRGIDFSISKGEKVGFLGRNGAGKSTLIRIISGAELPDSG
SVTRTMSVSWPLAFGGAFQNALTGVDNLRFICRIYGADLAGKLEYVEEFTELGRDLYEPL
RSYSAGMRARLAFAISMVIEFDCFLIDEVFAVGDDRFQRKCHVELFEKRADRAMIFVSHN
EWFVKDHCDRIAVLDKGLAVSCETVEESYEYYRARYG