Protein Info for GFF4231 in Xanthobacter sp. DMC5

Annotation: Putative aliphatic sulfonates-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details TIGR01728: ABC transporter, substrate-binding protein, aliphatic sulfonates family" amino acids 35 to 315 (281 residues), 254 bits, see alignment E=8.6e-80 PF04069: OpuAC" amino acids 35 to 238 (204 residues), 45.4 bits, see alignment E=1.7e-15 PF13379: NMT1_2" amino acids 42 to 257 (216 residues), 49.3 bits, see alignment E=1.2e-16 PF12974: Phosphonate-bd" amino acids 53 to 191 (139 residues), 38.2 bits, see alignment E=2.2e-13 PF09084: NMT1" amino acids 75 to 254 (180 residues), 62.9 bits, see alignment E=8.5e-21

Best Hits

KEGG orthology group: K02051, sulfonate/nitrate/taurine transport system substrate-binding protein (inferred from 88% identity to xau:Xaut_1211)

Predicted SEED Role

"Alkanesulfonates-binding protein" in subsystem Alkanesulfonate assimilation or Alkanesulfonates Utilization or Putative sulfate assimilation cluster

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (319 amino acids)

>GFF4231 Putative aliphatic sulfonates-binding protein (Xanthobacter sp. DMC5)
MSTGITRRHFAVLASGLAGALALGAAPARAQEKVVRIGYQKYGTLILLKNKGLLEPLLKP
LGYSVKWAEFPAGPQLLEALNAGAVDFGNTGEAPPIFAQAAGAPLVYVGYEPAAPQGEAI
LVPKDSPLKTVADLKGKTVALNKGSNVHYLLVKALEKAGVPYSDIKTAYLTPADARAAFE
RGSVDAWAIWDPFQAAAEKTIDARQLADGTGIVSNYQFYLSTRSFVDQAPQVVDVLLKGV
AEVGAWVKANPKAAAAEFSPLIGIPAPILEVALARQQYDVKPITPEVAAAQQQVADAFLA
LGLIPKPIRIADALRAPKS