Protein Info for GFF4190 in Sphingobium sp. HT1-2

Annotation: [Protein-PII] uridylyltransferase (EC 2.7.7.59) / [Protein-PII]-UMP uridylyl-removing enzyme

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 918 TIGR01693: protein-P-II uridylyltransferase" amino acids 61 to 905 (845 residues), 944.6 bits, see alignment E=2.8e-288 PF08335: GlnD_UR_UTase" amino acids 211 to 349 (139 residues), 154.3 bits, see alignment E=4.5e-49 PF01966: HD" amino acids 491 to 589 (99 residues), 41.9 bits, see alignment E=2.2e-14

Best Hits

KEGG orthology group: K00990, [protein-PII] uridylyltransferase [EC: 2.7.7.59] (inferred from 92% identity to sjp:SJA_C1-35020)

Predicted SEED Role

"[Protein-PII] uridylyltransferase (EC 2.7.7.59)" in subsystem Ammonia assimilation (EC 2.7.7.59)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.7.59

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (918 amino acids)

>GFF4190 [Protein-PII] uridylyltransferase (EC 2.7.7.59) / [Protein-PII]-UMP uridylyl-removing enzyme (Sphingobium sp. HT1-2)
MQFPSLGSRRAIIDRRAISDSINALAQEHRGDPIKLRGLIVKELKAALEHGREDVARRLE
AKPTRGREAVTAFAFLIDQILRLLYDATTHHLYPAGNRSTGERIVLIAVGGYGRGEMAPH
SDVDIGFITPWKPTGWTEQIIESMLYSLWDLGLKVGHSSRSIDETMRMAKADLTVRTALL
EARYVWGDRALYEEVAVRFDSEIMQGTARTFVTEKLEERDERHRRMGDSRYVVEPNVKEG
KGGLRDLHTLFWIGKYVNRVKSVAELVDVGLLTQSELRQFQKAEDFLWAVRCHLHMITGR
AEDRLTFDLQLETATRMHFTARAGRSGVERFMRYYFLNAKAVGDLTAVFLAHLDDQLAER
GRRYIPSIFRRPKKLDGFVLDRGRLALPSDDFFQADPVRLVEIFAVADRHGLQIHPSAMR
AASRDAGLITAKVRKDARANAAFMDVLTSPRDPETVLRWMNESTVFGRFIPDFRRVVAQM
QFDMYHHYTVDEHTIRAVGLLARIEKGELATDHPLATELMGKILSRRVLYVAVLLHDIAK
GRGGDHSILGAEVAEHLCPRLGLTAAETETVAWLVRYHLLMSATAFKRDLADYKTILDFV
EVVQSPERLRLLLCLTVVDIRAVGPGVWNSWKRQLLGDLYDAAEEVLRLGHKQKGRSERV
AAKQEALRQALGMDEATFAAFSGRMPESYWIAEPDDILVHNARHILEAGDSSLSIAAQYY
PQRGATLVTVYATDHPGLFYRIAGAIHLAGGNIIDARIHTTRDGVAIDNFLVQDPLGGAF
HSPEQLARIKAAIEDSLSNRHRMITKLEARPLPRTRAEAFRIEPNVLIDNKASNRFTVIE
VNARDRPALLFSLANALFQSKVTVHSAHVATYGERAVDTFYVTDLLGGKIESKARLQTLE
RRLLEAAGGEVGEALERA