Protein Info for GFF419 in Xanthobacter sp. DMC5

Annotation: Deoxyribodipyrimidine photo-lyase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 PF00875: DNA_photolyase" amino acids 6 to 170 (165 residues), 153.7 bits, see alignment E=4.4e-49 PF03441: FAD_binding_7" amino acids 278 to 476 (199 residues), 304.3 bits, see alignment E=3.3e-95

Best Hits

Swiss-Prot: 49% identical to PHRA_AGRFC: Deoxyribodipyrimidine photo-lyase (phrA) from Agrobacterium fabrum (strain C58 / ATCC 33970)

KEGG orthology group: K01669, deoxyribodipyrimidine photo-lyase [EC: 4.1.99.3] (inferred from 80% identity to xau:Xaut_4676)

Predicted SEED Role

"Deoxyribodipyrimidine photolyase (EC 4.1.99.3)" (EC 4.1.99.3)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.99.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (491 amino acids)

>GFF419 Deoxyribodipyrimidine photo-lyase (Xanthobacter sp. DMC5)
MTAAPSLLWFRDDLRLADNPALNALAETGAPIAALYVLDEDSPHIRPLGAAARWWLAQSL
RALRADLSHHGIPLILRQGPATRIVPEVAAALGAATVAFNDRAGEAEGKLDRAITARLAA
EDRRVLHFCAHLLHPPGTVLGGSGRMPRTFSSFHRAALRERDLSPPLPAPKRLKGVTRAP
EGDTLESFALEPEKPDWAGGLRTAWHVGEAAARQRLSAFIADGLKGYATGRDRPDLEHVS
RLSPHLRFGEMSPRQIFFAVRHAVDAGEVPGSDAAKFEAELYWREFSYHLLAEDPDIARR
NIQQSFDAFPWRECSGELKAWRRGLTGYPLVDAGMRQLWQTGWMHNRVRMVVASFLAKHL
LIDWRAGEDWFWDTLVDADAANNAASWQWVAGSGLDAAPYFRIFNPVMQGEKFDPDGTYV
RTYVPELKRLPAKLIHQPWTAPQDTLAAAGIRLGHTYPKPLVDHAAARDRALRAFEHLRH
AAPTEARAAAR