Protein Info for GFF4185 in Sphingobium sp. HT1-2

Annotation: DNA translocase FtsK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 774 transmembrane" amino acids 21 to 46 (26 residues), see Phobius details amino acids 72 to 94 (23 residues), see Phobius details amino acids 112 to 129 (18 residues), see Phobius details amino acids 136 to 154 (19 residues), see Phobius details amino acids 165 to 184 (20 residues), see Phobius details PF13491: FtsK_4TM" amino acids 29 to 180 (152 residues), 59.2 bits, see alignment E=8.8e-20 PF17854: FtsK_alpha" amino acids 276 to 376 (101 residues), 105.9 bits, see alignment E=2.2e-34 PF01580: FtsK_SpoIIIE" amino acids 386 to 602 (217 residues), 242.6 bits, see alignment E=7e-76 PF09397: FtsK_gamma" amino acids 709 to 766 (58 residues), 86.5 bits, see alignment 1.5e-28

Best Hits

KEGG orthology group: K03466, DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family (inferred from 90% identity to sjp:SJA_C1-35190)

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (774 amino acids)

>GFF4185 DNA translocase FtsK (Sphingobium sp. HT1-2)
MAVSRGAKRAPEWREMLKRSIVRSGALIGAISLFLATLFLALALLSYQPSDPSMNTVAGD
HVANIMRAPGAMVADMLLLLFGVPIALLLPLMGITARRLWGDHEMIGWKAQFGKCLVGII
LIGIALALFQPDPLVGLPSGWGGMIGLVTAKGVMSLTAQAPAAQGWIIGILVVVAMLAGL
FVWYRSLALEKPIFTIRRPTLPRLSLPRPSLAFAGQGGAADLDEDDDGPVERVIAPRKQV
SNEPKPPITIQAPKPAPVQRSTAPVSQDDLFGHSSLPSADLLNPIPANQGQKIDKAALER
NARLLESVLDDFHVKGNIVEVRPGPVVTMYELEPAPGIKASRVIALADDIARNMSALSAR
VATIPGRTVIGIELPNTNREGVSFRELITSEQFGAEATLPIILGKNISGEPIIADLAPMP
HLLIAGTTGSGKSVGLNAMILSLLYRMTPDQLRLIMIDPKMLELSTYDDIPHLLAPVVTE
PSKAIRALKWAVEQMEDRYRMMASISVRNLANYNEKVRAAKAKGKPLGRRVQTGYDPESG
KPIYEEEQLDFQPLPQIVVVVDELADLMMTAGKEVEFLIQRLAQKARAAGIHLILATQRP
SVDVITGVIKANLPTRISFFVTSKIDSRTILGEQGAEQLLGKGDMLYMHGGKGLMRVHGP
FVSDDEVRVVADHWRAQGSPDYIQAVTEEPEEGSFALDGVDLGDDSPDAQLFRKACQLVF
ENQKASTSWLQRQLRVGYNSAARLIERMEEEGLVGPPNHVGRREVLRDENGNPL