Protein Info for GFF4184 in Sphingobium sp. HT1-2

Annotation: Histone acetyltransferase HPA2 and related acetyltransferases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 163 PF00583: Acetyltransf_1" amino acids 41 to 137 (97 residues), 69.2 bits, see alignment E=5.9e-23 PF13673: Acetyltransf_10" amino acids 49 to 143 (95 residues), 26.6 bits, see alignment E=8e-10 PF13508: Acetyltransf_7" amino acids 52 to 137 (86 residues), 47.4 bits, see alignment E=3.1e-16

Best Hits

Swiss-Prot: 36% identical to SAT2_MOUSE: Diamine acetyltransferase 2 (Sat2) from Mus musculus

KEGG orthology group: None (inferred from 82% identity to sch:Sphch_2214)

Predicted SEED Role

"Histone acetyltransferase HPA2 and related acetyltransferases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (163 amino acids)

>GFF4184 Histone acetyltransferase HPA2 and related acetyltransferases (Sphingobium sp. HT1-2)
MSKVIIRDAQSTDIDTIANFILALADYEKLAHEVKADRETLARYLFGPRPMAEVLIAEHD
GAPIGFALFFHNFSTFEGRPGLYLEDLFVLPEARGLGAGKALLARLARLAIARDCARLEW
SVLDWNAPAIAFYRAIGARPMDEWTVQRVDGDALSALASHPAG