Protein Info for GFF4178 in Xanthobacter sp. DMC5

Annotation: Fumarate reductase flavoprotein subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 582 PF00890: FAD_binding_2" amino acids 16 to 387 (372 residues), 129.4 bits, see alignment E=3.2e-41 PF02910: Succ_DH_flav_C" amino acids 466 to 559 (94 residues), 54.1 bits, see alignment E=2.4e-18

Best Hits

KEGG orthology group: None (inferred from 94% identity to xau:Xaut_2801)

Predicted SEED Role

"Putative reductase (alkanesulfonate metabolism)" in subsystem Putative sulfate assimilation cluster

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (582 amino acids)

>GFF4178 Fumarate reductase flavoprotein subunit (Xanthobacter sp. DMC5)
MSAFDSEMKTEIVETDILVIGGGTGGPMAAIKAKEKNPGLKVVLMEKANVKRSGAVSMGM
DGLNNAVIPGYATPEQYVKEITVANDGIVHQKAVMAYATGSYPMIQYLDSIGVKFEKDGS
GEYNVRKVHHMGTYVLPMPEGHHVKKALYRQLRKHQVLVTNRYMATRLLTGTDGRVAGAI
GVNTRTGEFLVIRAKAVVLACGAAGRLGLPASGYLFGTYENPANCGDGYAMAYHAGAGLA
NLECYQINPLIKDYNGPACAYVTGPFGGYTANNKGERFIECDYWSGQMMKEFYGELLSGN
GPVFLNMTHLAEETISEIETILHSNERPSRGRFHEKRGTNYREKMVEMHISEIGFCSGHS
ASGVWVDENARTTVPGLYAAGDMASVPHNYMLGAFVNGGIAGEDAADYCASTDLPAYDAA
DVVREQARVMAPTRRDDGLTPFEMEYKARRLVNDYLQPPKVTAKYKIGQARLAEVRDDLS
ALCVKDPHELMRALELQSILDCADMAAAASLYRTESRWGLYHWRVDHPATDNENWFCHTL
LYKDEMGRMAHKKRAVDPYVVEIDEDEMGAYHQLRTPAIAAE