Protein Info for GFF4152 in Sphingobium sp. HT1-2

Annotation: Pyridoxal phosphate-containing protein YggS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 244 TIGR00044: pyridoxal phosphate enzyme, YggS family" amino acids 10 to 223 (214 residues), 161.8 bits, see alignment E=1e-51 PF01168: Ala_racemase_N" amino acids 17 to 223 (207 residues), 58.8 bits, see alignment E=3.5e-20

Best Hits

KEGG orthology group: K06997, (no description) (inferred from 83% identity to sch:Sphch_2238)

Predicted SEED Role

"Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (244 amino acids)

>GFF4152 Pyridoxal phosphate-containing protein YggS (Sphingobium sp. HT1-2)
MTTDIPEAAARLATLRDQIDRAARLTQRSADDINLIAVSKTQPAETILPLIHAGQRVFGE
NRVQESQDKWPALREQFSDLTLHLVGQLQSNKAADAVALFDVIHSLDRLSLLTALAKAMD
AAGKRLPCFIQVNIGAEEQKGGCPIADVPALIAAARDADIPLLGLMCVPPADVEPAPYFA
LLAKMAREEGLPRLSMGMSGDFETALMLGATDIRVGTALFGERAPVSRPVPRSGLGMIRN
APAR