Protein Info for GFF4146 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: putative inner membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 689 PF06048: DUF927" amino acids 130 to 413 (284 residues), 358.4 bits, see alignment E=1.8e-111

Best Hits

KEGG orthology group: K06919, putative DNA primase/helicase (inferred from 100% identity to seh:SeHA_C2917)

Predicted SEED Role

"putative inner membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (689 amino acids)

>GFF4146 putative inner membrane protein (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MKRAPFLCKQSPDRTLEVVILAGSLAWETSRVWRKDPDREDDVPPMVLGPNELADLSNLT
IIRPDTLYVRVLRTGDISEEDLLKIAVKLAHAGVQMARLMSPDGELLENWTGQLERLRQE
RPSDILPDHFRLDEEALWFDKLTERRDGESDVQPQRICSPLRVTAITCDSHDGSYGRLLE
WHTTTGQLRRWAMPMAMLSGNGEELRRILLENGLTNISTRPALRSLLCEYISRSLPGRRV
TCVEKTGWHNGVYVLPDEVIGPDGDNVILQGSHYLTGGFAQAGTLAEWQEQVAALCAGNS
RLVFAVCCALAAPLLRLTGTGGGGFHLRGESTDGKTTVMKVAASVCGGTDYWHSWRATGN
ALEGIASRHNDALLPLDELREVDPREAGMIAYMLANGQGKGRARTDGEVRNRRHWTLLLF
STGELSLAEHTERAGERIYAGMDVRMVQIPSDTGQHGAFEQLHGFASGQQFADTLCDRVA
RFHGTAFRAWLAFLTHDQDASTTLARELLRRYQNALMPDNAGNQVQRIVARFALLAAAGE
IATLHGITGWQKGTAYEAVQICLHAWLNERGHIANQEDEGVLAQIKRFITAHQYSRFASW
DGPDRPLNMAGFRRVEKDPLTGEEHTLFFILPEGWREICRGFSPARAARLCQEAECLQPG
SDGKYQSQVRLPEIGKTRVYRLTSRILSI