Protein Info for GFF411 in Sphingobium sp. HT1-2

Annotation: Uncharacterized UPF0118 membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 349 signal peptide" amino acids 1 to 15 (15 residues), see Phobius details transmembrane" amino acids 24 to 42 (19 residues), see Phobius details amino acids 53 to 75 (23 residues), see Phobius details amino acids 143 to 167 (25 residues), see Phobius details amino acids 197 to 226 (30 residues), see Phobius details amino acids 228 to 260 (33 residues), see Phobius details amino acids 263 to 281 (19 residues), see Phobius details amino acids 305 to 330 (26 residues), see Phobius details PF01594: AI-2E_transport" amino acids 4 to 331 (328 residues), 145.6 bits, see alignment E=1.1e-46

Best Hits

KEGG orthology group: None (inferred from 74% identity to sjp:SJA_C1-08080)

Predicted SEED Role

"membrane protein, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (349 amino acids)

>GFF411 Uncharacterized UPF0118 membrane protein (Sphingobium sp. HT1-2)
VFVALVVLVSIAFALVVEPFFGAILWGVIVAILFIPVNQGLLKLIPGHRNSAALLTLLLI
IAIVIVPAIILSIALVQEATALYAQINVGKINIPHMFAQFQAALPDWASIGLRRLGISNF
AAVQRLLTDGLTASFRTVAAQAFLIGQSAFSFLIALTVMLYLTFFLLRDGLDLTRKLDRA
APLRVLHRRALMRQFVIVIRATIKGSIVVAILQGLIGGLVFGALGISGALLWGVMMGFFS
LLPAVGTGLIWAPVAIYLLATGAIWKGLILIFCGMFVIGMVDNLLRPILVGRDTRIPDYV
VLITTLGGLQLFGFNGIVIGPVIAALFIATWQIVIRTRSNEAGAPPLTF