Protein Info for GFF4098 in Xanthobacter sp. DMC5

Annotation: Leucine-specific-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 404 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF13458: Peripla_BP_6" amino acids 30 to 381 (352 residues), 197 bits, see alignment E=1.1e-61 PF13433: Peripla_BP_5" amino acids 31 to 379 (349 residues), 61 bits, see alignment E=1.7e-20 PF01094: ANF_receptor" amino acids 76 to 255 (180 residues), 36.2 bits, see alignment E=5.6e-13

Best Hits

Swiss-Prot: 32% identical to LIVB5_BRUSU: Leu/Ile/Val-binding protein homolog 5 (BRA1193) from Brucella suis biovar 1 (strain 1330)

KEGG orthology group: K01999, branched-chain amino acid transport system substrate-binding protein (inferred from 57% identity to sfu:Sfum_2140)

Predicted SEED Role

"Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1)" in subsystem ABC transporter branched-chain amino acid (TC 3.A.1.4.1) (TC 3.A.1.4.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (404 amino acids)

>GFF4098 Leucine-specific-binding protein (Xanthobacter sp. DMC5)
MMHRRTLVKSVAALGLATLFGAGTAAAQEKIKIGAAVSLTGNFAREGHLLKNGYAYWEKL
VNDAGGIKVGDKKMPVEVIYYDDESKPQTSARLTEKLITEDGVGFILGPYSSGIATATAA
ISEKYKVITMTPMATADSLYQRGYKYIFCPAPLASTTLDPMLALLKTVKDPPKTIAIAGP
DDLFPNVFAGAAQKKAEAEGLKVVYSTKYPKGSADLSSVATALKESNPDVLILTGYVQDS
ILLIKTLQTLKVNPKLIGFAFAVGIPDFLNALGPAAEDLFGVQIWDPALTYKGPVVADSA
TYVETFKKQFGGEVPTYITAAGTAGALSLQLAIEKAGSIDPVKVREAMLQLDTDTFFGPV
KYNDAGVDVKASAVVAQVQGGKAVPVYPPAIAAAPVVYPRKPFP