Protein Info for GFF4095 in Xanthobacter sp. DMC5
Annotation: Bicarbonate transport ATP-binding protein CmpD
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 43% identical to TAUB_PSEPK: Taurine import ATP-binding protein TauB (tauB) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
KEGG orthology group: K02049, sulfonate/nitrate/taurine transport system ATP-binding protein (inferred from 68% identity to azl:AZL_a00790)Predicted SEED Role
"Taurine transport ATP-binding protein TauB" in subsystem Taurine Utilization
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (272 amino acids)
>GFF4095 Bicarbonate transport ATP-binding protein CmpD (Xanthobacter sp. DMC5) MNAATMHPKDQTYPPSYASPLLEVSGVTLQYKTRDLLVTATRDVSFEVYPADRFVLLGPS GCGKSTLLKGVAGFLKPVAGFMRLNGQMIDGAGPDRMMVFQDFDQLMPWKTVLENVMFPI LVSRRFPRAEARARAMASITKVKLGKFADAYPHMLSGGMKQRVAIARAMAMEPAILLMDE PFAALDALTRRQMQDELLQLWDDTRFTVLFVTHSIEEAIVVGSRILVLSPHPGQVKAELN AHQYGHDHQGGSDFMALSQKINTMLFAEGNHG