Protein Info for PS417_20975 in Pseudomonas simiae WCS417

Annotation: protein kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 556 transmembrane" amino acids 534 to 554 (21 residues), see Phobius details PF13672: PP2C_2" amino acids 11 to 186 (176 residues), 36.5 bits, see alignment E=7.7e-13 PF00069: Pkinase" amino acids 277 to 460 (184 residues), 108.4 bits, see alignment E=8.8e-35 PF07714: PK_Tyr_Ser-Thr" amino acids 280 to 500 (221 residues), 58.2 bits, see alignment E=1.6e-19

Best Hits

KEGG orthology group: None (inferred from 92% identity to pfs:PFLU4610)

Predicted SEED Role

"Serine/threonine protein kinase (EC 2.7.11.1)" (EC 2.7.11.1)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.11.1

Use Curated BLAST to search for 2.7.11.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UJC8 at UniProt or InterPro

Protein Sequence (556 amino acids)

>PS417_20975 protein kinase (Pseudomonas simiae WCS417)
MSLQLSVAQASAIGPRTENQDALRVVTPVAELAASKGYLCAIADGVSQCADGGLAARSTL
QALALDYYATPQTWGVAQALERLLLAQNRWLQANGGGQPLLTTLSALVFRGQRFTLAHVG
DCRAYRWFAGQLQRITEDHVWEQPGMQHVLKRALGLDQHLVVDFLDGQLREGECFLLVSD
GVWATLGDPSIQTILREQTDMELAVNTLVNAAHLAGSQDNASALLVRIDALGAATLGDAL
VQLQQWPLPPLLKAGQHFEGWQVESVLAQSRQSLLYRVRDAQQQPWLLKTLPLSRDDDHD
AGQALLSEEWFLRRVAGRAFPEVHAGSARQHLYYVMREYSGQTLAELFQRQGPLPLAQWQ
AIAERLLRAVGILHRRQILHRDLKPENLLLGEDGELRVLDFGLAYCPGLSEDHVHALPGT
PSFIAPEAFNGERPTTQQDLYSVGVTLYYLLTGHYPYGEIEAFQRPRFTQPVSASRYRPD
LPDWLPLSLERAVAAHPAHRYETAEEWLRVLEQADRQELSVRPKPLLEREPLKVWRTLAL
LSLLINLVLLYSLFHR