Protein Info for PS417_20955 in Pseudomonas simiae WCS417

Annotation: secretion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 483 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details TIGR02516: type III secretion outer membrane pore, YscC/HrcC family" amino acids 35 to 428 (394 residues), 299.3 bits, see alignment E=2.1e-93 PF21304: T3S_SPI-1_N0" amino acids 35 to 103 (69 residues), 78.2 bits, see alignment E=6.6e-26 PF03958: Secretin_N" amino acids 181 to 262 (82 residues), 38.6 bits, see alignment E=1.5e-13 PF00263: Secretin" amino acids 311 to 425 (115 residues), 35.4 bits, see alignment E=1.3e-12

Best Hits

KEGG orthology group: K03219, type III secretion protein SctC (inferred from 80% identity to pfs:PFLU4606)

Predicted SEED Role

"Type III secretion outermembrane pore forming protein (YscC,MxiD,HrcC, InvG)" in subsystem Type III secretion systems, extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7UDK0 at UniProt or InterPro

Protein Sequence (483 amino acids)

>PS417_20955 secretion protein (Pseudomonas simiae WCS417)
MHADFLATISFRRYCRWMLFSALLLGSALAWGTLYQAQDESLYTVLTALSEPLGLPIVVS
REVARKRLSAALDFNAPQQTLEALALQQGLIWYSDGQALYVYDAGEAKNSAVTLRHISVD
RLRSLKRRSGLDESRYPLRESGARTFYVSGPPNYIDQVLRLAQLMDRQRAELRVGAQSFA
VVQVLNTDVVDRQYGTRANPVTVPGMASMIETFLAGEHKGLLSDKSLGVIAYPDSNSLLI
KGKPAQVSFIQKLVAELDIPKRAIEVSLWLVDVEREELKKLGLAWDEETKASTTRVLAPL
DDSHLMAKVGALERRRRAKVTTLPVILTQENVPAVFQDNHTFYLPPRGDDRADWKPLRYG
TQVSVLPRFVEANQIEMRLEVEEGRLMSEASQRKKNAAVRQVGINSVVRVPQARRLWLGA
FQRESEGRGAGRPAQARLFVIQATAVGSESKGLEEAGGPPPMTAAQYERVQRAFVRPQRD
VSP