Protein Info for GFF4084 in Sphingobium sp. HT1-2

Annotation: UPF0126 inner membrane protein CC_3680

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 214 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 42 to 63 (22 residues), see Phobius details amino acids 70 to 90 (21 residues), see Phobius details amino acids 102 to 121 (20 residues), see Phobius details amino acids 127 to 147 (21 residues), see Phobius details amino acids 159 to 177 (19 residues), see Phobius details amino acids 183 to 200 (18 residues), see Phobius details PF03458: Gly_transporter" amino acids 18 to 90 (73 residues), 67.3 bits, see alignment E=4.5e-23 amino acids 102 to 174 (73 residues), 74.3 bits, see alignment E=2.9e-25

Best Hits

Swiss-Prot: 40% identical to YADS_AERCA: UPF0126 membrane protein (yadS) from Aeromonas caviae

KEGG orthology group: None (inferred from 80% identity to sch:Sphch_1135)

Predicted SEED Role

"YghA protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (214 amino acids)

>GFF4084 UPF0126 inner membrane protein CC_3680 (Sphingobium sp. HT1-2)
MLPPTPTIATHIGPVLEALSLIGTFVFGASGALAAARLRQTLVTFAFFALLTGVGGGTVR
DLLIDAPVFWIHDPAPSIVCMAAAITVWITPRRWWSDHALDWLDAIGLAAFAVFGAAKAM
SFGVPPFVAGMMGVVTGCVGGIMRDTLAGEPSILLRPELYVTAAAFASGLFVLLRLAGLD
VPVAGVIAALLGFGLRALAIRRGLGLPAYKEAGE