Protein Info for GFF4079 in Sphingobium sp. HT1-2

Annotation: Protein of unknown function DUF541

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 241 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF04402: SIMPL" amino acids 34 to 237 (204 residues), 191.7 bits, see alignment E=9.8e-61

Best Hits

Swiss-Prot: 34% identical to BP26_BRUSU: 26 kDa periplasmic immunogenic protein (bp26) from Brucella suis biovar 1 (strain 1330)

KEGG orthology group: K09807, hypothetical protein (inferred from 81% identity to sjp:SJA_C1-23090)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (241 amino acids)

>GFF4079 Protein of unknown function DUF541 (Sphingobium sp. HT1-2)
MKSALALMALGAAALPVAAVAQTSVTIAETAPVVTLNVTESVEAAPDVATIGTGVQTKAP
TAAQAMKDNAAKMDGLIAALAKAGIAKADIQTSGINLNAQYDYSNRDGQPSGPRFLGYEA
SNQLSVKVRDVKKVGALLDTLVQAGATNINGPSFSVEDPSPLQAQARATALKTAKAQADF
YAQAAGYRSARLVSISESSSGGNAPMPLMAARFKADAAPTPVEPGQVSASISLTVQYALE
R