Protein Info for GFF4058 in Sphingobium sp. HT1-2

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 transmembrane" amino acids 20 to 44 (25 residues), see Phobius details amino acids 57 to 78 (22 residues), see Phobius details amino acids 87 to 106 (20 residues), see Phobius details amino acids 112 to 134 (23 residues), see Phobius details amino acids 145 to 166 (22 residues), see Phobius details amino acids 172 to 195 (24 residues), see Phobius details amino acids 243 to 262 (20 residues), see Phobius details amino acids 273 to 296 (24 residues), see Phobius details amino acids 308 to 325 (18 residues), see Phobius details amino acids 331 to 353 (23 residues), see Phobius details amino acids 367 to 388 (22 residues), see Phobius details amino acids 397 to 418 (22 residues), see Phobius details PF07690: MFS_1" amino acids 26 to 383 (358 residues), 135.2 bits, see alignment E=1.4e-43 amino acids 271 to 418 (148 residues), 42.7 bits, see alignment E=1.8e-15

Best Hits

KEGG orthology group: None (inferred from 83% identity to sjp:SJA_C2-05520)

Predicted SEED Role

"MFS permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (429 amino acids)

>GFF4058 Uncharacterized MFS-type transporter (Sphingobium sp. HT1-2)
MLSTMFARRLAARNVHYGWAVAGTTFLTMLVVAGAVGAPGVFIIPLQKEFGWSAADISGA
LAIRFLLFGGMGPFAAAFMNRFGVRRMMLISLSIVIGGLLLSLGMTQLWQLVLLWGVVIG
VGTGLTAMVLGATVATRWFSERRGLVMGLLSASTATGQLAFLPLLASMTGNYGWRVAMLL
VCGAILVAAVAVMLLMRDRPSDLNLPPYGEQAIQPVPAQPASLGALLATPLIVLRDVAKV
PTFWILFFSFYICGASTNGLVQTHFISLCGDYGLAAVGAASMLAMMGLFDFAGTLASGWL
SDRYDNRWLLFFYYGLRGLSLLYLPFSDFSIYSLSLFAIFYGLDWVATVPPTVKLTAQRF
GPEKANIVFGWIFAGHQLGAASAALAGGLSRTAWQSYMPAFIAAGVLCLIGAALVLLINR
GRTPSLATA