Protein Info for GFF4055 in Xanthobacter sp. DMC5

Annotation: Cytochrome bd-I ubiquinol oxidase subunit 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 342 transmembrane" amino acids 12 to 42 (31 residues), see Phobius details amino acids 63 to 83 (21 residues), see Phobius details amino acids 89 to 109 (21 residues), see Phobius details amino acids 121 to 142 (22 residues), see Phobius details amino acids 157 to 185 (29 residues), see Phobius details amino acids 198 to 219 (22 residues), see Phobius details amino acids 234 to 256 (23 residues), see Phobius details amino acids 263 to 283 (21 residues), see Phobius details amino acids 303 to 325 (23 residues), see Phobius details PF02322: Cyt_bd_oxida_II" amino acids 12 to 328 (317 residues), 273.3 bits, see alignment E=1.4e-85 TIGR00203: cytochrome d ubiquinol oxidase, subunit II" amino acids 23 to 221 (199 residues), 125.3 bits, see alignment E=1.7e-40

Best Hits

KEGG orthology group: K00426, cytochrome bd-I oxidase subunit II [EC: 1.10.3.-] (inferred from 78% identity to sno:Snov_3536)

MetaCyc: 46% identical to cyanide insensitive ubiquinol oxidase subunit II (Pseudomonas putida KT2440)
RXN-6883 [EC: 1.10.3.11]

Predicted SEED Role

"putative Cytochrome bd2, subunit II" in subsystem Terminal cytochrome d ubiquinol oxidases or Terminal cytochrome oxidases

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.10.3.-

Use Curated BLAST to search for 1.10.3.- or 1.10.3.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (342 amino acids)

>GFF4055 Cytochrome bd-I ubiquinol oxidase subunit 2 (Xanthobacter sp. DMC5)
MTELMQADHVPLLFAAAALFCVTVYVLADGLDLGVGILFLAAPRDADRDVMMASIEPVWD
GNETWLVMGGTLLFAAFPAGYYILLPAFYLPIMFMLFALIFRGVAFGFRLQATRFRPVWD
AAFFAGSLLATFCQGLILGGLIDGVPVENGMFAGGAFSFLSVLGIMCGVGLVGGYALIGA
GWLIWKAQGPTQVFGREIARAALILTSAMMLLVSLWSAWSVPEVAARWFALPNLLWLAPV
PLLTLAVIVGIWWAIWNGREAQTFVLSLVLFALGLFGLVVSMWPYVVPRQVTVWDGLSDP
RSLAFLGVGVMVIIPVVLAYQAHAYWIFRGKVQHEAGHGGYG