Protein Info for PS417_20735 in Pseudomonas simiae WCS417

Annotation: cytochrome Cbb3

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 325 transmembrane" amino acids 6 to 25 (20 residues), see Phobius details amino acids 57 to 77 (21 residues), see Phobius details TIGR00782: cytochrome c oxidase, cbb3-type, subunit III" amino acids 34 to 319 (286 residues), 253.4 bits, see alignment E=1.4e-79 PF14715: FixP_N" amino acids 37 to 83 (47 residues), 83.9 bits, see alignment 7.5e-28 PF13442: Cytochrome_CBB3" amino acids 146 to 219 (74 residues), 44.9 bits, see alignment E=1.7e-15 amino acids 234 to 312 (79 residues), 41.9 bits, see alignment E=1.6e-14 PF00034: Cytochrom_C" amino acids 149 to 221 (73 residues), 32.2 bits, see alignment E=3.5e-11 amino acids 236 to 296 (61 residues), 34.4 bits, see alignment E=6.8e-12

Best Hits

KEGG orthology group: K00406, cb-type cytochrome c oxidase subunit III [EC: 1.9.3.1] (inferred from 99% identity to pfs:PFLU4561)

MetaCyc: 85% identical to cbb3-2 cytochrome c oxidase subunit P (Pseudomonas putida KT2440)

Predicted SEED Role

"Cytochrome c oxidase subunit CcoP (EC 1.9.3.1)" in subsystem Terminal cytochrome C oxidases (EC 1.9.3.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.9.3.1

Use Curated BLAST to search for 1.9.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U7D0 at UniProt or InterPro

Protein Sequence (325 amino acids)

>PS417_20735 cytochrome Cbb3 (Pseudomonas simiae WCS417)
MTTFWSLYVTVLSLGTIFALTWLLLSTRKGQRAEQTDETVGHSFDGIEEYDNPLPKWWFM
LFVGTIIFALGYLALYPGLGNWKGLLPGYSYLDNDKQTPFANGQTGWTGVHEWEKEMAKS
DAKFGPIFAKFASMPIEEVAKDPQALKMGGRLFASNCSVCHGSDAKGAYGFPNLTDADWR
WGGEPATIKETIMKGRHAVMPAWLDILKEQGVSDVAAFVVTNLDGRKLPEGVKADVANGE
KLFAANCVACHGPAGKGTPAMGAPDLTHPGAFIYGSSFAQLQQTIRWGRQGQMPAQEQLQ
GNDKVHLLAAYVYSLSHGDKKAEEQ