Protein Info for GFF4046 in Sphingobium sp. HT1-2

Annotation: anti-FecI sigma factor FecR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 transmembrane" amino acids 77 to 97 (21 residues), see Phobius details PF16220: DUF4880" amino acids 2 to 41 (40 residues), 34.7 bits, see alignment 1.3e-12 PF04773: FecR" amino acids 103 to 195 (93 residues), 75 bits, see alignment E=5.4e-25

Best Hits

KEGG orthology group: None (inferred from 82% identity to sch:Sphch_1019)

Predicted SEED Role

"regulatory protein PupR, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (326 amino acids)

>GFF4046 anti-FecI sigma factor FecR (Sphingobium sp. HT1-2)
LEAARLLARLNSDPTPQDEDEICAWIEADPRHGVAFARAEAAWDAAERLKSAAAEVNLPP
LEAIVSEEQQRRLSRNIMIAAGIAIAFFIVAAIVTIRTFSGVDRYETAVGQIRDVALADG
SILHLNSNSEAEVRFTDIGRKVRVLKGEASFDVAHDKGRPFDVEVRSAQIRAVGTAFNVR
MRPSVVELTVTQGTVTVHSGNSGLEKVSAGSGAVIQSRSIDLTHLSPKLIDQRTAWRDQM
VELDGETIEQAASEFNRYRRAPILIGDARVSSLRVGGRFRVSDSKEFLSALQLSLPIRAV
NGEDGSVMLLYRDEPDGADIMAAPSE