Protein Info for GFF4034 in Xanthobacter sp. DMC5

Annotation: Adaptive-response sensory-kinase SasA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 499 transmembrane" amino acids 21 to 38 (18 residues), see Phobius details amino acids 43 to 61 (19 residues), see Phobius details amino acids 66 to 87 (22 residues), see Phobius details amino acids 93 to 112 (20 residues), see Phobius details PF13188: PAS_8" amino acids 125 to 175 (51 residues), 25.4 bits, see alignment 3.1e-09 TIGR00229: PAS domain S-box protein" amino acids 126 to 242 (117 residues), 56.6 bits, see alignment E=1.4e-19 PF00989: PAS" amino acids 126 to 226 (101 residues), 35.4 bits, see alignment E=2.8e-12 PF08448: PAS_4" amino acids 128 to 236 (109 residues), 37.9 bits, see alignment E=5.6e-13 PF13426: PAS_9" amino acids 133 to 234 (102 residues), 32.8 bits, see alignment E=2.1e-11 PF00512: HisKA" amino acids 258 to 326 (69 residues), 36 bits, see alignment E=1.7e-12 PF02518: HATPase_c" amino acids 369 to 486 (118 residues), 85.4 bits, see alignment E=1.2e-27

Best Hits

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (499 amino acids)

>GFF4034 Adaptive-response sensory-kinase SasA (Xanthobacter sp. DMC5)
MSGLAGLLSSNRADAPARGRTGWVIVALLCLSIFLVDTLSPLDMAIAVLYVVVVLLSAGL
FGRTGLLIVAGACVMMTMLSFVIMHATDYNVSSTMRCFVSVAAITVTTVLSLRNQQATGA
LREQAALLDLSQDAIFVRNLADTIVYWNHGAERLYGWTRAEALGQQAGALLKTVFPSPRA
NIMGILLKTGQWEAEIVQTTRDGRKLVCTSRWSLQRDARGRPMGTMETNHDITERQKAEQ
ELNQVRSDLAHVTRVSTMGELTASIAHEVNQPLAAVVTNGEACLRWLRRPVADLGEAEAS
VTRMIANARRASEVVERLRAFARRGEPLRDALDSAELVEDCVLLLERELSNHRVRLELAL
APDLPRIEGDRIQLQQVLINLVLNAIQAMDEVPEGQRVLTVRNALETPTWSMDGTAELTI
SVRDTGPGIAPDVFASLFSPFVSTKQDGMGLGLSVSRSIAQAHGGRIDATPHPEGGMCFT
LTMPLASTPPSSNTRDTRP