Protein Info for GFF3999 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: Putative inner membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 transmembrane" amino acids 71 to 99 (29 residues), see Phobius details amino acids 149 to 168 (20 residues), see Phobius details amino acids 174 to 197 (24 residues), see Phobius details amino acids 218 to 251 (34 residues), see Phobius details amino acids 271 to 295 (25 residues), see Phobius details PF05661: DUF808" amino acids 4 to 290 (287 residues), 379 bits, see alignment E=7.4e-118

Best Hits

Swiss-Prot: 86% identical to YEDI_ECOLI: Inner membrane protein YedI (yedI) from Escherichia coli (strain K12)

KEGG orthology group: K09781, hypothetical protein (inferred from 98% identity to sew:SeSA_A2148)

Predicted SEED Role

"Putative inner membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (303 amino acids)

>GFF3999 Putative inner membrane protein (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
LAGSSLLTLLDDIATLLDDISVMGKLAAKKTAGVLGDDLSLNAQQVTGVRANRELPVVWS
VAKGSLINKVILVPLALLISAFIPWAITPLLMLGGAFLCFEGVEKVLHTFEARKHKEDPA
ERQKRLEALAAQNPLAFEKDKVKGAVRTDFILSAEIVAITLGIVAQAPLLNQVLVLAGIA
LVVTIGVYGLVGIIVKLDDMGYWLAEKRSVLAQGVGKGLLIIAPWLMKALSIVGTLAMFL
VGGGIVVHGIAPLHHAIEHFAQQQGAFMAHTIPAGLNLVLGFIIGAIVVALVKGVAKIRG
VSH