Protein Info for GFF3983 in Variovorax sp. SCN45

Annotation: ABC transporter, permease protein 2 (cluster 4, leucine/isoleucine/valine/benzoate) / ABC transporter, ATP-binding protein 1 (cluster 4, leucine/isoleucine/valine/benzoate)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 595 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 36 to 74 (39 residues), see Phobius details amino acids 82 to 105 (24 residues), see Phobius details amino acids 111 to 132 (22 residues), see Phobius details amino acids 157 to 177 (21 residues), see Phobius details amino acids 205 to 225 (21 residues), see Phobius details amino acids 245 to 269 (25 residues), see Phobius details amino acids 289 to 311 (23 residues), see Phobius details PF02653: BPD_transp_2" amino acids 30 to 299 (270 residues), 99.8 bits, see alignment E=2.3e-32 PF00005: ABC_tran" amino acids 363 to 521 (159 residues), 94.5 bits, see alignment E=1.3e-30 PF12399: BCA_ABC_TP_C" amino acids 571 to 593 (23 residues), 28.4 bits, see alignment (E = 1.4e-10)

Best Hits

KEGG orthology group: K01995, branched-chain amino acid transport system ATP-binding protein K01998, branched-chain amino acid transport system permease protein (inferred from 95% identity to vpe:Varpa_1662)

Predicted SEED Role

"Branched-chain amino acid ABC tranpsorter, permease/ATP-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (595 amino acids)

>GFF3983 ABC transporter, permease protein 2 (cluster 4, leucine/isoleucine/valine/benzoate) / ABC transporter, ATP-binding protein 1 (cluster 4, leucine/isoleucine/valine/benzoate) (Variovorax sp. SCN45)
MNGNRKRMAWIAGLVVVLALVPAVAGSFTVSLLNDIGIGALVALGLVLLTGVGGATSFGQ
AAFVGIAAYATAWLTTTQGMSPWIGLLFALLLTGVSALAIGMLTLRLGGHFLPLSTIAWG
LSIAMLFGNVDALGRHTGLSNIPPLQVAGWSLADPRAMYYLIWVVVGLACLFSHNLLQSR
PGRAIRGLRGGATLLASVGADAYRVRLSLFVTAALFAGLAGWLYAHMNRFVSPSPFDVRA
SIEYLLMAVAGGLGQLAGALVGAALVLVLKNGLQDVLPMLTQRAGQLEAVAFAALFILLL
HFARGGVMGLLRRWTRRRGSAREPSRHDAPPVEPLPHRTLPERGSQVLSVNGAVKRFGGL
VAVNDVSFDVKAGEIVGLIGPNGAGKSTMFNLLTCTLPMSSGQVRFLAHDIAGMPQREVA
RLGLARTFQHVKLRPHMSLLDNVALGAHSRTRSGILKAGLRLDRTEERQILQEAQRQLDR
IGLGDRAHELAGSLPLGTQRILEIARALAADPVLLVLDEPAAGLRRKEKMALGDLLRKLR
EEGVTILIVEHDMDFVMKLVDRLVVMNFGSKLVEGVPSAVRADERVQAAYLGSVV