Protein Info for GFF3957 in Hydrogenophaga sp. GW460-11-11-14-LB1

Annotation: GLUCOSE-FRUCTOSE OXIDOREDUCTASE (EC 1.1.99.28)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 387 PF01408: GFO_IDH_MocA" amino acids 50 to 134 (85 residues), 38.9 bits, see alignment E=2e-13 PF22725: GFO_IDH_MocA_C3" amino acids 149 to 289 (141 residues), 71.2 bits, see alignment E=1.2e-23 PF02894: GFO_IDH_MocA_C" amino acids 160 to 382 (223 residues), 44.1 bits, see alignment E=3.4e-15

Best Hits

Swiss-Prot: 56% identical to XDH_PAENI: D-xylose dehydrogenase (xdh) from Paenarthrobacter nicotinovorans

KEGG orthology group: None (inferred from 92% identity to vap:Vapar_1858)

Predicted SEED Role

"GLUCOSE-FRUCTOSE OXIDOREDUCTASE (EC 1.1.99.28)" (EC 1.1.99.28)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.99.28

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (387 amino acids)

>GFF3957 GLUCOSE-FRUCTOSE OXIDOREDUCTASE (EC 1.1.99.28) (Hydrogenophaga sp. GW460-11-11-14-LB1)
MAVQQLGIIMHGVTGRMGMNQHLIRSICAIRAQGGVTLSNGDRVMPDPILIGRNAEKMEA
LAKAHNIPRWGTDLDAALANKSDTIFFDAGTTQMRPTLLAKAIRAGKHVYCEKPIATNLN
EAVEIARLAEQSGLKHGAVQDKLFLPGLRKLDMLRRAGFFGRMLSVRLEFGYWVFEGDLQ
PIQRPSWNYRKEDGGGMILDMMCHWRYVLDNLFGEVKSVSCIGTTHIPTRWDEAGKPYEC
TADDAAYATAELTGHNGENVIAQLNMSWATRVNRDDLVTFHVDGTHGSAVATLTGCKAQS
RVNTPRPVWNPDVKQTMNFSEQWQDVPDTQVYDNGFKIQWEHFIRHVVENEPYKWTLPEG
AKGVQLVEAALESWEQRRWVDVPELKV