Protein Info for PS417_20260 in Pseudomonas simiae WCS417

Annotation: copper oxidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 568 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details TIGR01480: copper-resistance protein, CopA family" amino acids 4 to 566 (563 residues), 958.7 bits, see alignment E=1.2e-292 TIGR01409: Tat (twin-arginine translocation) pathway signal sequence" amino acids 5 to 32 (28 residues), 26.2 bits, see alignment (E = 7.2e-10) PF07732: Cu-oxidase_3" amino acids 53 to 163 (111 residues), 139.8 bits, see alignment E=6.8e-45 amino acids 459 to 566 (108 residues), 24.9 bits, see alignment E=2.8e-09 PF00394: Cu-oxidase" amino acids 172 to 344 (173 residues), 91.1 bits, see alignment E=1.3e-29 PF07731: Cu-oxidase_2" amino acids 450 to 567 (118 residues), 104.9 bits, see alignment E=4.6e-34

Best Hits

KEGG orthology group: None (inferred from 81% identity to pfo:Pfl01_3810)

Predicted SEED Role

"Multicopper oxidase" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7TZY7 at UniProt or InterPro

Protein Sequence (568 amino acids)

>PS417_20260 copper oxidase (Pseudomonas simiae WCS417)
MHSDTTRRTFVKGLAAGGLLGGLGLWRSPVWAVTSPGEPTVLAGTEFDLFIDQTPVNLTG
RHRTALTINGSLPGPLLRWREGDTVTLRVKNRLAEPTSIHWHGILLPSNMDGVPGLSFKG
IEPGGVFVYQFTVKQHGTYWYHSHSGFQEQQGVYGPLVIDPREPEPYTYQRDYVVMLSDW
TDEDPVALMKTLKKQSDYYNLHKPTMGDFVRDVGKQGWSATIADRLMWAQMKMNPTDLAD
VSGETYTYLLNGQPPERNWTGVFQAGETIRLRFINGSAMSYFDVRIPGLKMTVIAADGQP
VQPVGVDEFRIAVAETFDVLVEPTAEAYTLFAQSMDRSGYARGTLARQTGATAPVPALDP
RPWITMDDMGMGGMDHGAMADMPDMAGMDHSAMSMQAHPASEQDNPLVDMQAMSPVPKLD
DPGIGLRNNGRRVLTYADLRSTFEDPDGRDPSRTIELHLTGHMEKFAWSFNGVKFSDAEP
LQLAYGERVRLVLVNDTMMSHPIHLHGLWSDLEDENGQFQVRKHTIDMPPGSRRSYRVTA
DALGRWAYHCHLLYHMEMGMFREVRVHE