Protein Info for GFF3922 in Sphingobium sp. HT1-2

Annotation: HlyB/MsbA family ABC transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 560 transmembrane" amino acids 29 to 51 (23 residues), see Phobius details amino acids 63 to 88 (26 residues), see Phobius details amino acids 137 to 158 (22 residues), see Phobius details amino acids 164 to 183 (20 residues), see Phobius details amino acids 250 to 273 (24 residues), see Phobius details amino acids 279 to 297 (19 residues), see Phobius details

Best Hits

KEGG orthology group: None (inferred from 76% identity to npp:PP1Y_Mpl11053)

Predicted SEED Role

"Toxin secretion ABC transporter ATP-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (560 amino acids)

>GFF3922 HlyB/MsbA family ABC transporter (Sphingobium sp. HT1-2)
LASERFGLRQAAAWLSEVVGPDRSYVNVGIVYTVAISLLSLATPISVQLLINSVARTALV
APLWILSGVLLALLLVVAGLSALRVYLLAIFERRIFARVVAEITVRAVHAQNPFFVDESR
GSLFNRYFDMVIVQKSVPSLVIGAFTIVLQGAVGLVVTSFYHPFFLAFNLVLVTVCLMIW
LAWRHGAITGAVGVSHAKHNAAHWLESVGGSNGFYKSARHLNFAMDRSETVIADYIAAHR
RYFRYSFAQTLGYFLVYAFAAAALLALGGNLILAGQLSIGQLVAAELILSGVFYGIYQLG
SYLDTFYDLVASSEELSQILAIPQERLGQRGEAPRDGSVRFRDVEIDKAQINFEIASGEQ
AVILAEPGMESALALLLKRHAAPDSGIVLIGGSELGSFDMYLLRSAVMVLNRPTIIDVTL
REYLSFAEGRDMDGARIMNALERVGLGARLARLPHGLDTQLASSGSPLSIVEVMQLKLAN
ALLSRPRVLLLSQLYDMMPIASLKATLAELRAAGTTVLLSSGRPEALDLDAWYWVGARTQ
QRFTDKDEFARFVAAREAQP