Protein Info for GFF3899 in Sphingobium sp. HT1-2

Annotation: Ribonucleotide reductase transcriptional regulator NrdR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 141 TIGR00244: transcriptional regulator NrdR" amino acids 1 to 130 (130 residues), 159.1 bits, see alignment E=4e-51 PF22811: Zn_ribbon_NrdR" amino acids 1 to 30 (30 residues), 52 bits, see alignment 5.3e-18 PF03477: ATP-cone" amino acids 39 to 124 (86 residues), 73.6 bits, see alignment E=1.6e-24

Best Hits

Swiss-Prot: 74% identical to NRDR_SPHWW: Transcriptional repressor NrdR (nrdR) from Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)

KEGG orthology group: K07738, transcriptional repressor NrdR (inferred from 94% identity to sch:Sphch_0625)

Predicted SEED Role

"Ribonucleotide reductase transcriptional regulator NrdR" in subsystem Ribonucleotide reduction

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

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Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

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Protein Sequence (141 amino acids)

>GFF3899 Ribonucleotide reductase transcriptional regulator NrdR (Sphingobium sp. HT1-2)
VKDSRPTEDGNAIRRRRQCEACGARFTTFERIQLRDIWVVKSEGRKEAFERDKLARSIGI
ACRKRPIDPSRIEKLISGIQRQLETSGESEIPARSIGEMVMEGLKRLDSVAYIRFASVYK
DFTDARDFEDFASTVKEVGSE