Protein Info for GFF3893 in Sphingobium sp. HT1-2

Annotation: Similarity with glutathionylspermidine synthase (EC 6.3.1.8), group 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03738: GSP_synth
  • amino acids 12 to 377 (366 residues), 467.9 bits, E=1.3e-144

Best Hits

KEGG orthology group: K01917, glutathionylspermidine synthase [EC: 6.3.1.8] (inferred from 52% identity to nar:Saro_2359)

Predicted SEED Role

"Similarity with glutathionylspermidine synthase (EC 6.3.1.8), group 1" in subsystem Glutathionylspermidine and Trypanothione (EC 6.3.1.8)

MetaCyc Pathways

• glutathionylspermidine biosynthesis (1/1 steps found)

KEGG Metabolic Maps

• Glutathione metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 6.3.1.8

Protein Sequence (378 amino acids)

>GFF3893 Similarity with glutathionylspermidine synthase (EC 6.3.1.8), group 1 (Sphingobium sp. HT1-2)
MERIACTPRPHWQARVEHLGLVWHGADAQPYWDESACYRFSPDEIAEIELATAELYRLFL
AAGQHVLDQDLLGSFGIPDFCHQAIREAWDGEPAALNYGRFDLGYDGAGPPKLFEFNCDT
PTSLLEASVIQWDWKEAVFPAADQFNSLHERLVDRWRAIAPPRGTSMLHLTYVDGNMGED
AVTVAYMADTAREAGIDTQLIQTQQLGWDHQRRRFVDLDNRPIDALFHLYPWEWIVHEPF
GREVVESLSSTLWIEPIWKMIWSNKAILSILWDLFPGHPNLLEASRVAMTGDHVMKPLLS
REGANIRLVQDGETVAQSGGDYGEEGFIYQRLYTLPGAGDRRPVLGSWVVNGDPAGMGIR
EDGPITGNAARFVPHIIG