Protein Info for PS417_19925 in Pseudomonas simiae WCS417

Annotation: membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 294 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 34 to 54 (21 residues), see Phobius details amino acids 67 to 86 (20 residues), see Phobius details amino acids 92 to 113 (22 residues), see Phobius details amino acids 123 to 142 (20 residues), see Phobius details amino acids 149 to 166 (18 residues), see Phobius details amino acids 177 to 196 (20 residues), see Phobius details amino acids 207 to 231 (25 residues), see Phobius details amino acids 238 to 256 (19 residues), see Phobius details amino acids 262 to 281 (20 residues), see Phobius details PF00892: EamA" amino acids 10 to 136 (127 residues), 49.8 bits, see alignment E=2.2e-17 amino acids 148 to 278 (131 residues), 58.6 bits, see alignment E=4.1e-20

Best Hits

KEGG orthology group: None (inferred from 96% identity to pfs:PFLU4463)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U9Z6 at UniProt or InterPro

Protein Sequence (294 amino acids)

>PS417_19925 membrane protein (Pseudomonas simiae WCS417)
MTPRSALGALHIGALMFGLTGVFGKLAAASPAVIVFGRAAFAVVALAVFARFASNTAWKT
LELRDWRRLLVSGVLLAAHWVTFFIAVKVAGVAVATLGFTAFPAFTVILEGLIFRERIRA
NEVMLVALVSVGLVLVTPDFNVASEATSGLLWGIASGLLFSLLSLNNRASSGRIPAVQAA
LCQNVVVAVCLLPVAAPALADVRAIDWLWIGLLGVFCTGLAHSLFVASLAVIKARTASVV
FAMEPVYGITAAWLLFAETPTLRMLLGGALIIVAIVLSGLMGSASQAKQPAVTV