Protein Info for GFF3890 in Xanthobacter sp. DMC5

Annotation: Trehalose-6-phosphate synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 TIGR02400: alpha,alpha-trehalose-phosphate synthase (UDP-forming)" amino acids 3 to 455 (453 residues), 587.5 bits, see alignment E=9e-181 PF00982: Glyco_transf_20" amino acids 20 to 455 (436 residues), 434.6 bits, see alignment E=2.3e-134

Best Hits

KEGG orthology group: K00697, alpha,alpha-trehalose-phosphate synthase (UDP-forming) [EC: 2.4.1.15] (inferred from 83% identity to xau:Xaut_1721)

Predicted SEED Role

"Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC 2.4.1.15)" in subsystem Trehalose Biosynthesis (EC 2.4.1.15)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.15

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (491 amino acids)

>GFF3890 Trehalose-6-phosphate synthase (Xanthobacter sp. DMC5)
VSRIVVVSNRVALPQKSGAPAGGLAVAVNAALKDRGGIWFGWSGRIAPDPSDTPQETKHA
GVTYAVVDLTNEDYQEYYNGFANRVLWPVLHYRVDLSEFYRSDLSGYIRVNRMFADHLEK
IIRPDDILWIHDYHMMPLAKYLRERGHNNRIGFFLHIPMPPADIIQALPQHPDTVGALAY
YDLVGFQTEGDRENFARYLETRGGQSTPDGTGCDIGGRRVRLGTFPVGIETGAFARRARH
ASRTRFVKAFDESLSGRKLIIGVDRLDYSKGIPNRLDAYDQFLRKEPDWHDRVTFVQITP
KSRTDVPEYQDMDRSVSHRAGQINGAYSDVSWTPLRYVNRTYSRSALAGFYRRADVALVT
PLRDGMNLVAKEFVAAQDPEDPGVLLLSQFAGAASELGTGALIVNPHDTESVAAALRRAL
EMPLVERRDRHRRMMRVLEEHDINRWAEDFLAALEPDPQPERRDIALPRAAMRSVVRLPV
GWGSSALPRGA