Protein Info for GFF388 in Sphingobium sp. HT1-2

Annotation: Ubiquinone biosynthesis regulatory protein kinase UbiB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 513 transmembrane" amino acids 489 to 511 (23 residues), see Phobius details TIGR01982: 2-polyprenylphenol 6-hydroxylase" amino acids 8 to 439 (432 residues), 550.1 bits, see alignment E=1.6e-169 PF03109: ABC1" amino acids 91 to 337 (247 residues), 269 bits, see alignment E=3e-84 PF01636: APH" amino acids 138 to 311 (174 residues), 24.2 bits, see alignment E=2.6e-09

Best Hits

Swiss-Prot: 39% identical to UBIB_ACIAC: Probable protein kinase UbiB (ubiB) from Acidovorax citrulli (strain AAC00-1)

KEGG orthology group: K03688, ubiquinone biosynthesis protein (inferred from 91% identity to sjp:SJA_C1-08190)

Predicted SEED Role

"Ubiquinone biosynthesis monooxygenase UbiB" in subsystem Ubiquinone Biosynthesis

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (513 amino acids)

>GFF388 Ubiquinone biosynthesis regulatory protein kinase UbiB (Sphingobium sp. HT1-2)
MTTHATHIWRLLKWGRTLARHGALTGIERDPLTPTPVRRLVRLARFGARVPKQPRYADAF
QSIGPAAIKLGQTLATRPDLVGEEAANDLLRLQDALPPVPFDTIRAQVEQSFGRPLEQVY
ARFDEQPVGAASIAQVHRAVTSDGREVAVKVIRPGVIDQFNRDIQTYEWAAAHVEMLGGE
VARLRPRLVIANMKRWTARELDLRREAASASELAEAMEAMPGYRIPAIDWDRTTGKVMTM
EWIDGIKISDRDALIAAGHDLKDIAARLVNAFLRQAIAEGFFHADMHQGNLFVKGNGDIV
AIDFGIMGRIDRRARMWLAEILYGLITGNYKRVAEIHFEAQYVPGHHNVDEFATALRAVG
EPMRGKPASELSVGGMLDGLFAITRDFDMQTQPHLLLLQKTMVMVEGVAHQLDPEINMWE
TSGPYVKEWLRTELGPEAKAADALIENWRLIQRLPALVRRIEDAFPEKGGAPPPLPLGDV
KLIQVGGGWRYGLVALLAAAIGAGAMAAATTFF