Protein Info for PS417_19625 in Pseudomonas simiae WCS417

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 transmembrane" amino acids 21 to 37 (17 residues), see Phobius details amino acids 43 to 62 (20 residues), see Phobius details PF07730: HisKA_3" amino acids 86 to 150 (65 residues), 54.2 bits, see alignment E=1.8e-18 PF02518: HATPase_c" amino acids 193 to 280 (88 residues), 44 bits, see alignment E=2.7e-15

Best Hits

KEGG orthology group: None (inferred from 94% identity to pfs:PFLU4403)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1N7U4C2 at UniProt or InterPro

Protein Sequence (296 amino acids)

>PS417_19625 histidine kinase (Pseudomonas simiae WCS417)
MYASLKTLIARSASRSNARRLILALCLGSLLLSLWAYHFSAALPLLVMLNLTTLVVVGLQ
QWHSRKAIKFQPQELADRLLQVQENERHRLSRELHDDIGQLLTAAKLQSEWLKRRLPEDL
QSQCTVLCNTLNETLAKVRDVSAILNPRQLASLGLEASLRAHLLKTLENTQVCWSLECQQ
RLTGIPEEMAVAAFRITQEAVTNMLRHAQARNLLVRLQRLPEGLSLFISDDGQGFSPAIN
PGLEGQRGMAGMSERIDQLGGSLSVSSQPGKGTRIDALFPWAPRALERASSPKVLE