Protein Info for GFF3830 in Variovorax sp. SCN45

Annotation: Uncharacterized MFS-type transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 418 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 53 to 70 (18 residues), see Phobius details amino acids 78 to 98 (21 residues), see Phobius details amino acids 104 to 125 (22 residues), see Phobius details amino acids 138 to 159 (22 residues), see Phobius details amino acids 165 to 187 (23 residues), see Phobius details amino acids 223 to 243 (21 residues), see Phobius details amino acids 257 to 277 (21 residues), see Phobius details amino acids 288 to 307 (20 residues), see Phobius details amino acids 313 to 335 (23 residues), see Phobius details amino acids 347 to 367 (21 residues), see Phobius details amino acids 386 to 405 (20 residues), see Phobius details PF07690: MFS_1" amino acids 17 to 364 (348 residues), 113.2 bits, see alignment E=6.6e-37

Best Hits

KEGG orthology group: None (inferred from 85% identity to vap:Vapar_1368)

Predicted SEED Role

"major facilitator superfamily MFS_1"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (418 amino acids)

>GFF3830 Uncharacterized MFS-type transporter (Variovorax sp. SCN45)
MPGDNDAPIRGWLALLCASRLLQAMIVTAYSGVLPFMMADWHMTAAQAGSIQSAWHIGYM
SSLFAVGLLADRYGPHRIFFAGSAVSSMAALAFALFAHDHLSAMLLYGLAGLCAGASYTP
GLQLLARNTQPAVRGRAMGLFIGASSMGYALSLAVVAAFSHARHWPLGLLAAACCTVAGA
LLTVLALRRMRPPSAPLPHAEREGTWQALRATVHDKPAMAGNWAYAFHCWELMALWAWLP
AYLMASSGEASSSWQGAGVALAALAHLVSVFGSVAGGAASDRLGRARVMMAATLASLFMS
FAFGWMWTWPLWLLAAMAAVYNLCAIADSSVYSTALADVVAPHRLGVAFSVRSVMGFGAG
ALSPWVFGLALDWGQTRFGIGSTQGWVAAWSSVGLGALLGPWMIARFSRLHRARVAVH