Protein Info for GFF3818 in Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868

Annotation: HTH-type transcriptional regulator mlrA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 243 transmembrane" amino acids 134 to 155 (22 residues), see Phobius details PF13411: MerR_1" amino acids 4 to 72 (69 residues), 61.2 bits, see alignment E=8.2e-21 PF00376: MerR" amino acids 5 to 42 (38 residues), 45.2 bits, see alignment 6.5e-16

Best Hits

Swiss-Prot: 100% identical to MLRA_SALTS: HTH-type transcriptional regulator MlrA (mlrA) from Salmonella typhimurium (strain SL1344)

KEGG orthology group: None (inferred from 99% identity to set:SEN2154)

Predicted SEED Role

"HTH-type transcriptional regulator mlrA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (243 amino acids)

>GFF3818 HTH-type transcriptional regulator mlrA (Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868)
MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFNDADIDRIREIKRWIDNG
VQVSKVKVLLSSDSSEQPNGWREQQEILLHYLQSSNLHSLRLWVKERGQDYPAQTLTTNL
FVPLRRRLQCQQPALQALLGILDGILINYIALCLASARKKQGKDALVIGWNIHDTTRLWL
EGWVASQQGWRIDVLAHSLSQFRPELFDGKTLLVWCGENQTLAQQQQLLAWRAQGRDIHP
LGV