Protein Info for GFF3802 in Sphingobium sp. HT1-2

Annotation: Uncharacterized amino acid permease, GabP family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 465 transmembrane" amino acids 30 to 51 (22 residues), see Phobius details amino acids 57 to 77 (21 residues), see Phobius details amino acids 89 to 111 (23 residues), see Phobius details amino acids 113 to 127 (15 residues), see Phobius details amino acids 149 to 168 (20 residues), see Phobius details amino acids 179 to 199 (21 residues), see Phobius details amino acids 224 to 244 (21 residues), see Phobius details amino acids 257 to 284 (28 residues), see Phobius details amino acids 306 to 328 (23 residues), see Phobius details amino acids 356 to 375 (20 residues), see Phobius details amino acids 381 to 400 (20 residues), see Phobius details amino acids 412 to 432 (21 residues), see Phobius details amino acids 438 to 456 (19 residues), see Phobius details PF13520: AA_permease_2" amino acids 25 to 452 (428 residues), 201.9 bits, see alignment E=1.8e-63 PF00324: AA_permease" amino acids 29 to 444 (416 residues), 136.5 bits, see alignment E=1.2e-43

Best Hits

KEGG orthology group: K03294, basic amino acid/polyamine antiporter, APA family (inferred from 89% identity to sch:Sphch_1641)

Predicted SEED Role

"amino acid transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (465 amino acids)

>GFF3802 Uncharacterized amino acid permease, GabP family (Sphingobium sp. HT1-2)
MSWTRRKPMEAMTPQGGGDSMARTLSWPHLLALGVGAIVGTGILTLIGVGADRAGPAVLI
SFAIAGAICACAALAYAELSTMMPAAGSAYSYSYVVLGEGIAWIVGWSLILEYSLVVSTV
AVGWSGYAAPLLTPLGFPEALTKGPELGGFINIPAIFIIGVVAALLMFGTRESARLNTLL
VLIKIATLSLFVWVALPAFDAQHLEPFMPFGFAKHMGPDGIERGVMAAAAIIFFAFYGFD
AISTAAEEAKNPDRDLAIGIVGSLIVCTLIYVLVAAAAVGAMPFTRFADSPEPLALILRE
MGQGSIARIVAIAAVIALPTVLLGFLYGQSRIFLVMARDGFLPQSLARISKRGTPARITA
VTAVLVAIIAGVLPIDQIAALANAGTLIAFTAVGACLLILRRRAPDLKRPFRTPAATLVG
LGAVLGCAYLFLSLPMKTIYACLIWNAIGLVVYFLYGQKRASAAR