Protein Info for PS417_19375 in Pseudomonas simiae WCS417

Annotation: LysR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF00126: HTH_1" amino acids 5 to 64 (60 residues), 80.8 bits, see alignment E=5.5e-27 PF03466: LysR_substrate" amino acids 90 to 292 (203 residues), 168 bits, see alignment E=2e-53

Best Hits

KEGG orthology group: None (inferred from 95% identity to pfs:PFLU4351)

Predicted SEED Role

"LysR family transcriptional regulator clustered with dicarboxylate transport" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See U1V1I1 at UniProt or InterPro

Protein Sequence (298 amino acids)

>PS417_19375 LysR family transcriptional regulator (Pseudomonas simiae WCS417)
MKNSIQHIQAFLAVARTGSFTKAANELHLSPSALTVQVQQLEDWLGVALLDRSPRHVSIT
AAGQDARGPMEKLLLDLDNIVTGSRDLAALRRGVVTIAALPSVCAGALPPVLRLFRERFA
GIEVRLHDLVAHRIHAQVRSGEVDFGIGVRARLSHGLEFVPVLNDRLCAFVPLDHPLTRF
PQLTLEQLADQPIILTGRDSSVREQVDALFDQTRLTLNAGMEANYMSTVLALVRQGLGIS
VLPESAADSLEGLKRINIEHPGVNREIGLISRSGMGLSPAAQRCFDLLHDELPDTPLS