Protein Info for GFF378 in Xanthobacter sp. DMC5

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 transmembrane" amino acids 47 to 69 (23 residues), see Phobius details amino acids 82 to 103 (22 residues), see Phobius details TIGR01620: TIGR01620 family protein" amino acids 57 to 321 (265 residues), 229.6 bits, see alignment E=2.4e-72 PF05128: DUF697" amino acids 167 to 324 (158 residues), 156.6 bits, see alignment E=2.3e-50

Best Hits

Swiss-Prot: 57% identical to Y7254_BRADU: UPF0283 membrane protein blr7254 (blr7254) from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)

KEGG orthology group: K08990, putative membrane protein (inferred from 81% identity to xau:Xaut_3784)

Predicted SEED Role

"GTP-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (335 amino acids)

>GFF378 hypothetical protein (Xanthobacter sp. DMC5)
MSDERNSPRRPQVFRLDEANITLAPPEMAEVEAALPVPVPPKRGWGLSLAGLFWSALGGV
LSLAAYVGLSKLVEDLYARAPWLGWVGIGITALLLIAAVLIIAREVAGLSRLARLDDIRE
RAERALAADDRPLAEGVVKDVLKLSSHAPTLARARMDLEGHLSGIIDGADLVRLAERTLL
PSLDAQARQMVSDAARNVSVVTAVSPRAAVDLAFVLYSAVTLMRRLAYLYGGRPGTLGTF
RLVRHVLGHLAVTGGMAAGDTLVQQIVGQGLAARLSARLGEGVVNGLLTARLGLAAIAVT
RPLPFTALPAPRLSDVATGLMRKAEEEETVASRRQ