Protein Info for GFF3779 in Xanthobacter sp. DMC5

Annotation: Peptidyl-lysine N-acetyltransferase PatZ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 902 PF13380: CoA_binding_2" amino acids 13 to 138 (126 residues), 68.9 bits, see alignment E=2.2e-22 PF13607: Succ_CoA_lig" amino acids 156 to 293 (138 residues), 178.1 bits, see alignment E=3e-56 PF13549: ATP-grasp_5" amino acids 483 to 704 (222 residues), 302.3 bits, see alignment E=7.4e-94 PF13302: Acetyltransf_3" amino acids 737 to 871 (135 residues), 46.2 bits, see alignment E=3e-15 PF00583: Acetyltransf_1" amino acids 775 to 870 (96 residues), 53.9 bits, see alignment E=8.3e-18 PF13508: Acetyltransf_7" amino acids 789 to 871 (83 residues), 35.5 bits, see alignment E=4.3e-12

Best Hits

KEGG orthology group: K09181, hypothetical protein (inferred from 84% identity to xau:Xaut_1742)

Predicted SEED Role

"Protein acetyltransferase" in subsystem Pyruvate metabolism II: acetyl-CoA, acetogenesis from pyruvate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (902 amino acids)

>GFF3779 Peptidyl-lysine N-acetyltransferase PatZ (Xanthobacter sp. DMC5)
MTTRNLDALFHPRAIALVGASNRTGTVGALAARNLFEAGFEGPILSVNPKERAIRSSLNY
ASVADLPIPVDLAVVAAPPDEVPRVISQLGEKGCRAAVVLPAGYGPGEQFEGAEQRQALL
DAARPHLLRIIGPNGLGFISSRAHVNASIAHLMPAKGDVAFVSQSDTMTAAVLDWAHARG
FGFSHVAALGEKADVDFGDLLDYLALDNTTRAILLYVESIADARKFMSAGRIAARAKPVI
VIKAGRSVAGAQAALSHTGVLAGSDLVFDAALRRAGMLRVHEMRELFEAVTTLSAGIRLA
GERLAILTNGGGAGVVAVDALEGSAGRLGTLLPATVEALDKALPRTWSRSNPVDIQADAD
GARYGTALKALLADKGSDAVLVLHAPNALSDSSAAADGVMAVLETRPRAPVLTCWLGESA
AASARRRFAGRRIPTYDTPDEAVRAFGHLVAYQRNQTLLMETPPARSFDEPDRPAARRLV
EGVLAAGRSALTEVEAKAVLAAYDIPVVDTRIATSPEEAGRLAQDIGFPVVVKVLSHDLT
HKSDVGGVRLDLRTSAAVEDACRAIIASVAEKRPGARVEGFTVQAMIRRPNAQELIAGIG
YDKTFGPVVLFGQGGTAVEVIGDRAVALPPLNGVLAREMIERTRVAKLLAGYRDHPPADM
NAVAGTLVKVAELLADLPQIAELDINPLLADEHGVLALDARIVVHPTRVEGTDRFAIKPF
PSDLSKTLELTDGSTVALRPIRPEDEPGLVDVVHRSDPQDVRMRFLGSVKDFPHLMAARL
SQIDYDREMAFVAQEDNGDICGVVRIIADPDNDAAEYAIMVRSDFKGKGLGFQLMSEILA
HARKRGLRQVFGDVMRENGPMLRLAEDLGFKATPGSDDPSVMRVVLNLDVPSAVGVQIPE
EA